Gentamicin Sulfate Cream

Active Ingredients: Gentamicin Sulfate

Gentamicin Sulfate Cream is an antibiotic drug used to treat minor infections of the skin like impetigo or folliculitis. It is also used to treat skin infections caused by minor wounds or certain skin conditions like eczema or psoriasis. This medication is safe to use in adults and children over 1 year old.

Gentamicin is classified as an aminoglycoside antibiotic. It works by inhibiting protein synthesis within the bacteria. This product is used for treating primary and secondary bacterial infections of the skin. It is mainly used when patients do not respond to other topical antibiotics. In primary skin infections it is used for treating impetigo contagiosa, while in secondary skin infections, it helps in treating dermatoses by controlling the infections. The most sensitive bacteria and Streptococci (group A beta-hemolytic, alpha-hemolytic), Staphylococcus aureus (coagulase positive, coagulase negative, and some penicillinase-producing strains), and the gram-negative bacteria, Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris, and Klebsiella pneumoniae.

Gentamicin is also available for distribution as a cream or eye ointment. The eye ointment formulation is intended to treat infections in the eyes or the skin around the eyes. It is indicated for conditions like conjunctivitis, keratitis, blepharitis, and otitis externa.

This product is also available in a form as an injection.

AdvaCare Pharma is a trusted exporter of Gentamicin Sulfate Cream. Our supply chain is thoroughly vetted to ensure it meets health, safety, and environmental standards. This medication is produced in our GMP-certified manufacturing facilities in China, India, and the USA.

AdvaCare Pharma is a US pharmaceutical company that manufactures Gentamicin Cream, and our entire range of 50+ topical treatments in cream, ointment and gel dosage forms, under stringent GMP regulations. Our distinctive approach to business fosters a highly collaborative relationship with our pharmaceutical distributors. For the past 20 years we have established a reputation as a trusted Gentamicin manufacturer, one of the 500+ pharmaceutical products in our comprehensive range, across more than 65 global markets.

What is Gentamicin used for?

It is used to treat bacterial infections like: • skin infections like impetigo or folliculitis

How is Gentamicin Sulfate Cream used?

This medication is manufactured as a sterile cream or ointment, which is intended for topical administration directly to the skin. Do not use it in the nose, mouth, vagina, or rectum.

What dose should be applied?

Apply only enough ointment to cover the afflicted area, 2-3 times per day. Always wash hands with soap and water before and after using this medication.

Only a small amount of this cream should be applied only to the affected area. The area sometimes can be covered with gauze if a doctor suggests it.

In cases of impetigo contagiosa, the crusts should be removed before application. This allows maximal contact between the antibiotic and the infection.

Cases of overdose with this product are not common. Accidental oral ingestion might lead to an overdose. If accidental ingestion occurs, gastrointestinal symptoms such as diarrhea and vomiting may manifest, and these should be managed symptomatically. If you suspect an overdose of this product due to accidental ingestion, promptly inform your healthcare provider.

There is no data available about the dosing in geriatric, and pediatric patients. There is also no data available about dosing in patients with liver or renal impairments. Consult with a doctor to get personalized advice based on your current health condition.

Refer to a doctor or healthcare professional for the exact dosage and duration of treatment.

Who can use Gentamicin Sulfate?

This cream is recommended for wet, oozing primary infections, and also greasy, secondary infections (acne or infected seborrheic dermatitis). This product retains moisture and it is useful in an infection on dry eczematous and psoriatic skin. Special considerations should be made in the following groups of patients before using this product.

Pregnant women This product is considered safe for pregnant women and is not associated with any side effects. However, Pregnant women or those intending to become pregnant should inform their doctors about all current products they are using, including Gentamicin Sulfate. Adequate data regarding the safety and effectiveness of this product specifically in pregnant women is lacking.

Nursing This cream is also considered safe for breastfeeding women. When given in other forms it enters human milk, but this is a product that is applied topically and adverse effects are not expected for the infant. Nursing women should consult with their doctor if they are using or planning to use this product.

Pediatric There is not enough data available about the safety and efficacy of this ointment in pediatric patients. It is generally safe for all patients, but a consultation prior to application with a doctor should be made. If children develop some side effects after the initial application of this product, the usage should be limited.

Geriatric There is no data available about the usage of this product in geriatric patients. If you belong to the age group over 65 years of age you should consult with a doctor before using this product.

Is only this product enough to treat some skin issues?

This product is efficient in the treatment of ecthyma, furunculosis, superficial folliculitis, impetigo contagiosa, sycosis barbae, and pyoderma gangrenosum which all belong to primary skin infections. It can also help in the treatment process of secondary skin infections like Infectious eczematoid dermatitis, pustular acne, pustular psoriasis, infected seborrheic dermatitis, infected contact dermatitis (including poison ivy), infected excoriations, and bacterial super-infections of fungal or viral infections. This product is not effective against viruses or fungi in skin infections, in such cases, antifungal and antiviral drugs need to be included for the patient.

In some cases only this product can lead to complete recovery, however it all depends on the severity of the skin issue. Very often supplements can be prescribed to improve skin health and integrity. This usually includes vitamin A and zinc.

Other warnings

The skin should be protected from further contamination after applying this cream.

The most common side effects include irritation like erythema and pruritus. If this occurs, patients should report it to a healthcare professional and another alternative antibiotic cream should be chosen.

Photosensitization can occur in some patients.

In some rare cases, an overgrowth of nonsusceptible organisms might occur. This includes fungal infections.

This product is not effective against viruses or fungi. In cases of viral or fungal infections, doctors should prescribe adequate treatment.

In cases of an accidental overdose, patients should seek immediate help. Gastrointestinal symptoms like vomiting or diarrhea need to be treated as soon as possible.

As with all pharmaceuticals, some unwanted effects can occur from the use of Gentamicin Sulfate Cream.

Common side effects include, but may not be limited to: • skin redness and itching

The most common side effects are occasional allergic reactions which include stinging, burning, itching, or redness. Consult with a doctor if you suspect any of these side effects.

For a comprehensive understanding of all potential side effects, consult a medical professional.

If any symptoms persist or worsen, or you notice any other symptoms, please call your doctor.

Gentamicin Nitrate Ointment should be used with caution in pregnant women or breastfeeding mothers. Consult a doctor or healthcare professional before treatment.

Topical antibiotic creams bring a risk of overgrowth of nonsusceptible organisms like fungi. When this happens, patients should report it to a healthcare professional and the treatment should be discontinued. Appropriate therapy like antifungal drugs should be given and the patients should be treated based on the cause of the infection.

Patients that are allergic to aminoglycoside antibiotics should inform their doctors and another topical antimicrobial should be chosen.

This product should be stored at room temperature and away from children and pets.

Application of topical gentamicin—a new era in the treatment of genodermatosis

Gentamicin topical cream has antimicrobial activity and has been used in the treatment of hereditary diseases. The main objective of this study was to evaluate the topical application of gentamicin and its use in genetic skin diseases.

The study was performed by analyzing different databases using the key search terms “gentamicin, topical gentamicin, genodermatosis, genetic skin diseases”.

The results of this study showed that the application of gentamicin in genodermatosis led to promising results, both in vivo and in vitro, including Nagashima-type palmoplantar keratosis, epidermolysis bullosa, Hailey–Hailey disease, hereditary hypotrichosis simplex of the scalp, etc.

This study indicates that topical gentamicin is a potential treatment option for genodermatosis caused by nonsense mutation.

A Clinical Comparison of Tobramycin and Gentamicin Sulfate in the Treatment of Ocular Infections

This study evaluates the safety and efficacy of tobramycin and gentamicin sulfate ophthalmic solutions in the treatment of patients with bacterial infections of the conjunctivas.

This is a double-masked study that included 66 patients.

The conclusion of this study is that these two aminoglycosides were found to be equally safe and effective.