Pharmaceuticals: Therapeutic Class

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Pharmaceutical manufacturer of tablets, capsules, injections, suspensions, creams, drops.

Standards

  • 9001
    Quality Management
  • 14001
    Environmental Management
  • 45001
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Certifications

  • GMP
  • ISO
  • WHO-COPP
  • FSC
  • COA
  • COO

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  • CTD Dossier
  • Site Master File
  • Bioequivalence (BE) Studies

Manufacturing Locations

  • China, India, United States
*Regulatory compliance may vary according to production standard, import requirements and/or manufacturing origin.
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What is the meaning of Musculoskeletal Pain Medication?

Musculoskeletal pain medication helps with pain and inflammation caused by musculoskeletal conditions and effectively improves mobility and quality of life. Treatments for musculoskeletal disorders target conditions that affect the muscles, bones and joints, like osteoarthritis, fibromyalgia, and other chronic pain conditions. More common muscle conditions, such as treatment for pain relief of the lower back, are also managed with many of the same pain medications.

There are several types of musculoskeletal pain treatments, including nonsteroidal anti-inflammatory drugs (NSAIDs), opioids, and muscle relaxants.

What is Musculoskeletal Pain Medication used for?

What Are Musculoskeletal Medicines used to treat?

Musculoskeletal pain medication is used for back pain relief and other musculoskeletal pain conditions. Some of the most common indications for musculoskeletal pain treatment include: - Back pain - Neck pain - Sprains and strains - Arthritis - Tendinitis - Bursitis - Fibromyalgia - Gout - Osteoporosis - Muscle spasms and cramps

What is the mechanism of common Musculoskeletal Medicines?

Treatments for musculoskeletal disorders act by various mechanisms to reduce pain, inflammation, and stiffness associated with musculoskeletal disorders. Most commonly, they target the cyclooxygenase (COX) enzyme, which is responsible for producing prostaglandins that cause inflammation, pain, and fever. By inhibiting COX, these drugs reduce inflammation and pain.

Another common mechanism of musculoskeletal medications is to target the pain signal transmission pathways in the central nervous system. By blocking the transmission of pain signals from the site of injury to the brain, pain perception is reduced.

Medication for musculoskeletal pain may also have muscle relaxant properties, which help reduce muscle spasms and stiffness. Some drugs may target specific types of pain, such as neuropathic pain, which is caused by damage to the nerves.

Types of Musculoskeletal Pain Medication

Musculoskeletal pain medication is used for back pain relief and other symptoms associated with the bones and joints. There are many different bone diseases and conditions that can be treated with musculoskeletal medications.

Bone Diseases

Musculoskeletal medications used to treat bone diseases affecting structure and mineralization focus on promoting bone formation, inhibiting resorption, and regulating mineral metabolism.

Calcitonin is an important component in musculoskeletal medicines. It is a hormone that regulates calcium and phosphate metabolism. Synthetic calcitonin is used to treat conditions such as osteoporosis, Paget's disease, chronic recurrent multifocal osteomyelitis, and pseudogout, a type of arthritis. It inhibits osteoclast activity and reduces the destruction of bone tissues. Calcitonin also provides analgesic effects for individuals with bone pain associated with certain bone disorders.

Osteoporosis

Osteoporosis is a skeletal disorder characterized by decreased bone density and deterioration of bone tissue, leading to increased bone fragility and susceptibility to fractures. It occurs when the rate of bone resorption exceeds the rate of bone formation, resulting in a net loss of bone mass. The condition is often asymptomatic until a fracture occurs, with common sites of fracture including the spine, hip, and wrist.

Bisphosphonates, such as alendronate, risedronate, and ibandronate, are common examples of musculoskeletal osteoporosis medications. These drugs work by inhibiting osteoclast activity, reducing bone resorption, and slowing down bone loss. By binding to the bone surface, bisphosphonates help increase bone mineral density and decrease fracture risk. Osteoporosis medications may be indicated for postmenopausal osteoporosis, male osteoporosis, and glucocorticoid-induced osteoporosis.

Gout

Gout is a type of inflammatory arthritis characterized by the deposition of uric acid crystals in joints and surrounding tissues. It is caused by elevated levels of uric acid in the blood, known as hyperuricemia. When uric acid levels exceed the body's ability to eliminate it, uric acid crystals can form and trigger an immune response, leading to painful and swollen joints. Gout commonly affects the big toe but can also involve other joints, such as the ankles, knees, wrists, and fingers. The condition can be recurrent and is often associated with factors such as dietary choices, genetics, obesity, and certain medical conditions. The primary method of gout treatment involves the use of nonsteroidal anti-inflammatory drugs (NSAIDs) to alleviate pain and inflammation during acute attacks. Long-term management includes the use of gout medications that help lower uric acid levels in the blood, such as colchicine - a common component used in gout treatment and prevention. Such gout medications work by interfering with the inflammatory response triggered by the presence of uric acid crystals in the joints. Colchicine also reduces the activity of white blood cells, which helps alleviate pain and inflammation.

List of common Musculoskeletal Pain Medication

Musculoskeletal pain medication and drugs for bone diseases cover a large variety of indications. The following list provides common examples of active ingredients used in treating these types of medical conditions.

Bone Diseases

- Baclofen (BacloCare™) - Calcium carbonate - Cholecalciferol (VitD3Care™) - Ergocalciferol - Raloxifene - Calcitonin - Teriparatide - Abaloparatide - Denosumab

Osteoporosis

- Alendronate (AlendoCare™) - Zoledronic acid (ZoledroCare™) - Risedronate - Etidronate - Ibandronate

Gout

- Colchicine (ColCare™) - Allopurinol (AllopurCare™) - Febuxostat - Probenecid

Why choose us as your manufacturer of Musculoskeletal Pain Medication?

AdvaCare Pharma has been in the business of providing sustainable and affordable medical products for more than 20 years. Our investment in improving global healthcare means that our product range, including over 4,000 branded pharmaceuticals, medical devices, supplements, and veterinary products, is of high quality and compliant with stringent GMP guidelines and ISO standards. AdvaCare Pharma is a manufacturer of Musculoskeletal pain medications, producing and distributing multiple treatments for musculoskeletal disorders, back pain relief and bone diseases.

By aiming for high-quality, affordable products and customized market-specific solutions, AdvaCare Pharma provides the best value for our distributors and their customers. Having implemented a "vested supplier-distributor relationship", we work closely with our distributors ensuring a mutually beneficial outcome.