Folic Acid Tablets

Folic Acid Tablets help support red blood cell production and prevent birth defects. Taking folic acid before and during pregnancy can help reduce the risk of complications such as premature birth and low birth weight. It may also help reduce the risk of stroke by reducing homocysteine levels in the blood.

AdvaCare Pharma takes pride in producing high-quality, scientifically formulated prenatal supplements, including folic acid supplements. All supplements indicated for pregnancy nutrition purposes are manufactured in facilities that comply with rigorous HACCP and ISO standards to ensure absolute safety, purity and efficacy.

As a reliable manufacturer of Folic Acid Tablets, AdvaCare Pharma USA is dedicated to offering superior products and supporting our distributors and partners in attaining success in their target markets.

Our prenatal supplements under the AdvaLife™ brand have earned the endorsement of medical experts worldwide. As a trusted folic acid supplement manufacturer, our ISO 22000, 9001, and HACCP certifications demonstrate our unwavering focus on quality and consistency.

Folic Acid benefits pregnant women

This supplement is recommended for pregnant women and women who are trying to get pregnant. It can lead to normal fetal development and can prevent pregnancy complications. It can prevent preeclampsia and also neural tube defects like spina bifida.

Folic Acid benefits the cardiovascular health

Folic acid may promote heart health and potentially lower the risk of heart disease. Elevated levels of the amino acid homocysteine are linked to an increased risk of heart disease. Folate assists in the breakdown of homocysteine, and inadequate folate levels can lead to elevated homocysteine levels, known as hyperhomocysteinemia.

Folic Acid benefits the brain function

This supplement plays a role in brain health and development through its involvement in the synthesis of amino acids, the building blocks of proteins, including neurotransmitters. It can support the cognitive function, and can reduce the risk of age-related cognitive decline.

Folic Acid benefits anemic patients

This product is involved in the production of red blood cells and can improve overall oxygen delivery. It is beneficial in cases of folate deficiency anemia and is included in the production of red blood cells.

Folic Acid is a B-vitamin that plays an essential role in supporting overall health and wellness in various ways, particularly in cell growth and development. It is often recommended for women who are trying to conceive or are pregnant to help prevent birth defects of the brain and spine.

Folic acid also helps produce red blood cells and aids in the proper functioning of the nervous system. It may also have potential benefits in reducing the risk of certain cancers, such as colon and breast cancer. Moreover, folic acid deficiency may lead to anemia, fatigue, and weakness, which can negatively impact overall health and quality of life.

What are Folic Acid Tablets used for?

• support heart health
• promote red blood cell production
• help prevent birth defects

How are Folic Acid Tablets used?

This supplement is to be swallowed with water.

What dose of Folic Acid should be taken?

The recommended dosage of folic acid is 1 tablet daily, preferably with food, or as directed by a healthcare practitioner.

Do not exceed the recommended dosage. A laxative effect may occur in case of overdose.

Is Folic Acid available in other forms?

This supplement is also available in a syrup form. This product is a formulation of iron, folic acid, and ascorbic acid.

Why is Folic Acid recommended?

This supplement is very beneficial and can help people who lack folate in their diets. However, it should not be used as a substitute for some food. It is also beneficial for patients who have undergone surgery and whose bodies fail to absorb folate. Folic acid is also recommended for people with celiac disease, short bowel syndrome, and those who have had a recent gastric bypass surgery. It is advised for people with achlorhydria and hypochlorhydria.

If you have a pre-existing medical condition and you are taking methotrexate and sulfasalazine, this supplement is recommended for you because it can normalize the folic acid levels in the blood.

People who excessively consume alcohol can take this supplement. Pregnant women and people with hemolytic anemia can additionally benefit from this product.

It can prevent issues like anemia, fetal development disorders, mental impairments, impaired immune function, and depression.

Can only this supplement prevent birth defects and pregnancy complications?

According to studies, folic acid can prevent neural tube irregularities like spina bifida and anencephaly. This supplement is recommended during pregnancy, especially in countries where malnutrition is very common. It can also prevent complications like preeclampsia. However, other supplements, lifestyle changes, and dietary changes are recommended for pregnant women to prevent complications.

How can this supplement protect cardiovascular health?

Folate-based supplements can contribute to heart health and potentially reduce the risk of heart disease. Elevated levels of the amino acid homocysteine are associated with an increased risk of heart disease. Folate aids in the breakdown of homocysteine, and insufficient folate levels can result in elevated homocysteine levels, a condition known as hyperhomocysteinemia.

Supplementing with folic acid helps lower homocysteine levels and potentially reduces the risk of heart disease.

Is this supplement effective in cases of anemia?

Yes, folic acid is beneficial in cases of folate deficiency anemia. It can increase the production of red blood cells and can improve oxygen delivery.

Are there any side effects of Folic Acid?

Side effects usually occur when the supplement is taken at a dosage higher than the recommended dosage. The most common side effects are stomach upset, skin reactions, diarrhea, nausea, irritability, confusion, and behavior changes. Contact a healthcare provider if you notice any of these side effects.

How should this supplement be stored?

Folic acid tablets should be stored in a cool, dry location, shielded from direct sunlight, and kept out of the reach of children. It is important to safeguard the packaging from contamination to preserve the quality of the supplement.

As with all dietary supplements, some unwanted effects may occur from taking Folic Acid Tablets.

These supplements may not be suitable for people with certain diseases. Those who are pregnant, breastfeeding, diagnosed with any medical condition, or taking any medications must consult with a healthcare professional first.

What is the study for Folic Acid's impact on rheumatoid arthritis?

Folic acid is often recommended for people with rheumatoid arthritis because they regularly take methotrexate which is a disease-modifying antirheumatic drug (DMARD). It is because methotrexate inhibits the folic acid metabolism when taken regularly. This can lead to folate deficiency and many side effects like gastrointestinal symptoms, liver toxicity, and hematologic abnormalities.

Supplementation with Folic Acid during Methotrexate Therapy for Rheumatoid Arthritis: A Double-Blind, Placebo-Controlled Trial

The main objective of this study was to evaluate the effect of two different weekly doses of folic acid on the toxicity and efficacy of low-dose methotrexate therapy for rheumatoid arthritis.

It is a randomized, double-blind, placebo-controlled study. This research included 79 people between the ages of 19 and 78 years of age who fulfilled the American Rheumatism Association's criteria for rheumatoid arthritis.

All patients randomly received visually identical placebo or folic acid (5-27.5mg) each week. Some measurements were taken during the study including the duration, intensity, and clinical severity of toxic events. Also, the efficacy (indices of joint tenderness and swelling and grip strength); plasma, and erythrocyte folate levels.

Supplementation with folic acid at any dosage did not impact the effectiveness of methotrexate therapy, as assessed by joint indices and evaluations from both patients and physicians regarding disease status. However, participants receiving folic acid supplements had lower toxicity scores compared to those receiving a placebo (P ≤ 0.001). Low levels of blood folate and elevated mean corpuscular volumes were linked to significant methotrexate toxicity, while daily dietary intake exceeding 900 nmol (400 µg) of folic acid was associated with minimal methotrexate-related toxicity.

The conclusion of the study is that folic acid is an inexpensive vitamin that is safe in a broad range of doses and protects patients with rheumatoid arthritis. It is especially recommended for patients who are taking methotrexate. It can protect people from the drug’s toxicity while preserving the efficacy of methotrexate.

What is the evidence for Folic Acid's impact on cognitive function?

This water-soluble vitamin B is included in many physiological processes like DNA synthesis, repair, and methylation. It can lead to optimal brain function and cognitive health, especially in ageing adults. It can be beneficial in cases of Alzheimer’s disease and dementia. This vitamin can reduce the homocysteine levels which is associated with the progress and risk of dementia. Many studies prove this.

Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial

Decreased folate levels and elevated homocysteine concentrations in the bloodstream are linked to poor cognitive performance in the general population, but especially in older people. This is a FACIT trial that assessed the effect of folic acid on markers of atherosclerosis in men and women. It included people from 50 to 70 years of age with raised plasma total homocysteine and normal levels of vitamin B12. It discusses the effects of folic acid supplementation on cognitive performance.

It is a randomized, double-blind, placebo-controlled study that was taken in the Netherlands. It lasted from November 1999 to December 2004. It included 818 participants who received oral folic acid or placebo capsules for 3 years. A differentiation was measured between the two groups based on the performance for memory, sensorimotor speed, complex speed, information processing speed, and word fluency. Participants taking folic acid experienced a substantial increase in serum folate concentrations by 576% (95% CI 539 to 614) and a significant decrease in plasma total homocysteine concentrations by 26% (95% CI 24 to 28) compared to those receiving placebo.

During these 3 years, there was a significant improvement in memory (difference in Z scores 0.132, 95% CI 0.032 to 0.233), information processing speed (0.087, 95% CI 0.016 to 0.158), and sensorimotor speed (0.064, 95% CI -0.001 to 0.129) in the group that was taking folic acid supplementation compared to the placebo group.

The conclusion of this research is that folic acid supplementation for 3 years can significantly improve cognitive function, which tends to decline with age.