Praziquantel + Pyrantel Pamoate + Febantel Tablets

Active Ingredients: Praziquantel, Pyrantel Pamoate, Febantel

Praziquantel + Pyrantel Pamoate + Febantel Tablets are a broad-spectrum dewormer drug used to treat and control parasitic infections in dogs or puppies. This combination offers a safe and effective treatment for a broad spectrum of parasites, such as ascarids, whipworms, hookworms, and tapeworms.

These tablets contain three active ingredients with different mechanisms of action. This effectively treats many types of worms, including Toxocara canis, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma caninum, Trichuris vulpis, Echinococcus spp., Taenia spp., and Dipylidium caninum.

Praziquantel is a pyrazine isoquinoline derivative. This compound causes severe damage to the parasite's integument, which results in the contraction and paralysis of the parasites.

Pyrantel Pamoate is a tetrahydropyrimidine derivative. It works by depolarizing neuromuscular function, which leads to the paralysis of the worm. Pyrantel pamoate targets hookworms and ascarids by affecting the cholinergic receptors of the nematode, which leads to spastic paralysis. The peristaltic action of the intestinal tract expels the parasite from the body.

Febantel is an organic compound classified as a diaryl thioether. It is metabolized to Fenbendazole. It is thought to work by interfering with energy metabolism within the parasite. It is effective against nematode parasites, including whipworms. It is quickly absorbed and metabolized within the animal. It disrupts the parasite's energy metabolism, causing a breakdown in energy exchange and hindering glucose uptake.

This product contains three active ingredients with different modes of action and spectrums of activity. Praziquantel specifically targets cestodes (tapeworms). After absorption and metabolism in the liver, praziquantel is excreted in bile. Once in the digestive tract, it exhibits its ability to kill tapeworms. Following exposure to praziquantel, tapeworms lose their natural resistance to digestion by the host mammal. Whole tapeworms, including their scolices, are rarely passed after praziquantel administration. Instead, stool typically contains disintegrated and partially digested pieces of tapeworms. Most tapeworms are digested and do not appear in the feces.

Laboratory efficacy and clinical studies have shown that each of the three active ingredients operates independently without mutual interference. This combined tablet formulation offers a broad spectrum of activity against the specified species of intestinal helminths.

It is important to note that Praziquantel + Pyrantel Pamoate + Febantel Tablets are for veterinary purposes only.

AdvaCare Pharma is a global distributor and manufacturer of Praziquantel + Pyrantel Pamoate + Febantel Tablets. This medicine is produced in our GMP-certified facilities in China, India, and the USA.

Praziquantel + Pyrantel + Febantel Tablets, manufactured and globally supplied by AdvaCare Pharma, are one of our 250+ veterinary medicines. From supply chain coordination to product registration support, our professional teams of specialists and experts provide our veterinary distributors unparalleled support. As a trusted Praziquantel + Pyrantel + Febantel Tablets manufacturer, veterinarians and farmers alike rely on our high-quality veterinary tablets manufactured according to GMP standards.

What is Praziquantel + Pyrantel + Febantel used for?

What animals can be treated with Praziquantel + Pyrantel + Febantel?

This medicine is recommended for dogs and puppies.

How are Praziquantel + Pyrantel + Febantel used?

This medicine has been manufactured as a tablet, which is intended to be given orally to an animal. These tablets may be administered with a small amount of food. This drug does not require fasting prior to treatment.

In cases when reinfections occur, owners should aim for prevention, because in other cases, retreatment might be necessary. This is especially true in cases of Dipylidum caninum where reinfections occur frequently. For controlling Echinococcus multilocularis, a program of regular treatment every 21 to 26 days is required.

How does Praziquantel + Pyrantel + Febantel help in cases of Echinococcus multilocularis?

This is a parasitic infection that affects wild animals, but it can be also transmitted to domesticated dogs and humans. The adult tapeworm is between 1 and 4mm and it resides in the intestinal tract of the host. The eggs of the parasite are then shed in the feces, and rodents can transmit this disease to dogs. After canines consume a rodent infected with the cysts, the larvae within the cyst develops into adult tapeworms and affect their intestinal tract. The eggs can be passed in the feces of the canid in around 28 days later.

The diagnosis of this disease is difficult because the adult tapeworms produce no clinical signs of infection. Dogs that are diagnosed with this disease should be immediately treated with this drug to prevent the exposure of humans to infective eggs and to break the parasite’s life cycle. The recommended therapeutic dose leads to 100% efficacy, and if the dog is exposed to wild rodents, re-treatment at 21- to 26-day intervals is recommended to prevent the shedding of infectious eggs.

Is only this drug effective in treating E. multilocularis?

No, other measures need to be taken. Strict hygienic precautions should be taken when handling dogs that are infected. The animals should be retreated at intervals of 28 days. Infected animals should also be separated from healthy animals and their feces should be incinerated or autoclaved. Other possibilities are soaking the feces in sodium hypochlorite solution of 3.75% or greater concentrations. All areas where the animals were should be thoroughly cleaned with sodium hypochlorite to prevent the spreading of the disease.

Which clinical signs can be treated with Praziquantel + Pyrantel + Febantel Tablets?

This medication aids in solving the symptoms that arise from these infections. It can help in the treatment process of signs like lethargy, weight loss, diarrhea, colic, lack of appetite, and dull coat. It can also improve the results of the blood tests and biochemical parameters.

Is this drug effective in cats?

According to a study, this three-compound drug can help in the treatment process of Toxocara cati, and its efficacy is over 98%. This product is specifically for dogs, and owners should consult with a veterinarian before including it for cats.

What should be done if a dose is missed?

If a dose of this drug is missed, the next scheduled dose should to be given. Do not give double doses of this drug.

How should Praziquantel + Pyrantel + Febantel be stored?

This medication should be stored in a dark, dry location below 25°C. Keep the tablets in the blister pack when not in use.

How many Praziquantel + Pyrantel + Febantel should be given to dogs or puppies?

The usual dose is 1 tablet per 10kg of body weight. Do not use it for dogs weighing less than 3kg.

For prevention as a routine treatment, only one treatment is necessary. For a serious infestation, treatment may be repeated after 14 days.

Refer to a veterinary doctor or pharmacist for guidelines on dosage.

As with all pharmaceuticals, some unwanted effects can occur from the use of Praziquantel + Pyrantel Pamoate + Febantel Tablets.

Some side effects may include but are not limited to diarrhea, loss of appetite, vomiting, and fatigue. Serious side effects may include allergy or hypersensitivity reactions. If any side effects arise, it should be reported to a veterinarian.

For a comprehensive list of all possible side effects of this medication, consult a veterinarian.

Interactions have been recorded with organophosphate or diethylcarbamazine. Do not administer it concurrently with piperazine.

This drug should not be used in pregnant animals because in early pregnancy it might lead to increased incidence of abortion and fetal abnormalities.

The dosage should be determined by a veterinarian based on the animal’s body weight and the purpose for giving this drug. If a dose is missed, it should proceed to the next scheduled dose.

Owners should discuss with their veterinarian how to prevent human infection and re-infection of the pet. Strict hygienic measures should be taken when handling the infected pets and their feces.

If the animal is infected with tapeworms, owners might notice the expelling of the bowel movement through feces. Hookworms and roundworms might be visible in the feces a few days after the treatment.

To maximize the benefits of this drug, all animals in the surrounding need to be treated with this drug. Consult with a veterinarian before including all the animals in the treatment procedure.

Periodic fecal exams need to be performed to observe the efficacy of the treatment procedure. Notify your veterinarian if you do not observe any improvements.

Praziquantel + Pyrantel Pamoate + Febantel Tablets are mainly used for treating tapeworms, hookworms, and ascarids.

Dogs Parasitic Infections

This drug is used for treating Dipylidium caninum, Taenia pisiformis, Echinococcus multilocularis, and removal and control of Echincoccus multilocularis. It can also be used for removal of Ancylostoma caninum, Uncinaria stenocephala, Toxocara canis, Toxascaris leonina, and Trichuris vulpis.